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It also ameliorates oxidative stress and inflammation in various tissues, including the kidneys of diabetic rats 143,144,145 (Fig

doi: 10.1016/s0140-6736(05)78428-2

1,103,104,105 Once liver damage occurs, activated KCs begin to produce TNF- via Toll-like receptor (TLR)/MyD88-mediated pathways, which triggers the expression of immediate early genes involved in switching hepatocytes from a quiescent state to a dividing state

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RT-PCR analysis HCT116 dTAG-SNIP1 cells and its derivative stable cell lines expressing F-SNIP1 variants (WT, K265G, K265GK301G and E366G) were treated for 2 h with DMSO or 500 nM dTAG-V1