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GLP-1 agonists (Semaglutide, Tirzepatide, Retatrutide) are stable for approximately 28 days after reconstitution

En ellos se ha observado un incremento de la tolerancia al ejercicio en pacientes con angina de esfuerzo 26 , mejora en la sintomatologa 27 en pacientes con infarto de miocardio reciente, mejora de parmetros hemodinmicos y otros (patrn lipdico), atenuacin de la dilatacin del ventrculo izquierdo en el postinfarto 28 e incluso disminucin de la mortalidad 29

References: Pharmacokinetics and Tolerability of a Single Dose of Semaglutide, a Human Glucagon-Like Peptide-1 Analog, in Subjects With and Without Renal Impairment Semaglutide s.c

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Optimal results typically develop with continued use as part of a healthy routine