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This has fostered the emerging field of immunometabolism that is focused on investigating the pro-inflammatory cytokines and mediators of obesity, the metabolic syndrome, and T2D (74)

[,] Considering these difficulties, prevention of the disease becomes even more valuable, as it is often preferable to prevent a disease rather than seek a cure for it

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as such, senolytics do not require continuous presence in the circulation

The chosen specificity effectively reduced IgG recycling in cells and the IgG plasma half-life in relevant human transgenic mice and NHPs both as a full-length IgG4 and as other monovalent Fab-containing molecules [124]