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Received: 16 Sep 2024 | Accepted: 23 Nov 2024 | Published online: 30 Dec 2024 Key words GLP1, GLP-1RAs, cardiovascular disease, atherosclerosis, diabetes In 2008, Food and Drug Administration (FDA) mandated that cardiovascular safety assessments are necessary for all new anti-diabetic drugs, leading to evaluation of all newly developed glucose-lowering therapies in cardiovascular outcome trials on regular basis [6]