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& Owens, T
At 20% bioavailability (achievable with optimized cyclodextrin formulations in human studies), the equivalent nasal dose drops to approximately 20mg
However, given the TMAO elevating effect of oral L-carnitine supplementation, whether or not L-carnitine is a reasonable therapy to reduce Lp(a) levels requires further long-term investigations with hard clinical endpoints such as AMI, stroke and mortality risks
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