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They also reported that SH-SY5Y cells are resistant to a ferroptosis inducer (erastin) while highly sensitive to an apoptosis inducer (staurosporine

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ATF4 activation upregulates GSH and dTTP pools in T315I-Bcr-Abl-32D cells Next, we want to address the questions of what causes the increases in dTTP and GSH biosynthesis in T315I-Bcr-Abl and whether blocking the upregulation of these two factors can increase JMF4073 sensitivity

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