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As described in the CY 2026 PFS proposed rule (90 FR 32666), we proposed a related provision in new 425.600(h)(3), applicable for agreement periods beginning on or after January 1, 2027, under which, if an ACO is determined to have fewer than 5,000 assigned beneficiaries in either the first benchmark year, the second benchmark year, or both, in accordance with 425.110(a)(3) (as proposed to be revised), the ACO may only enter the BASIC track

They serve different needs, different populations, and different goals

However, we prefer subcutaneous administration over intramuscular injection, especially for frequent self-injection

Multi-dose vials, in particular, require extra attention to storage conditions to ensure they remain safe to use over time

Learning basic dosage guidelines and safety considerations helps people better understand how peptide therapy protocols are usually structured