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Much of the supporting data derives from animal models or correlative clinical observations, and therefore, this concept must be interpreted with caution ( Although considerable progress has been made in understanding the interplay between mitochondrial dysfunction and FAO disorders in HF, several limitations remain

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428,429,430 The unconventional protein secretion pathway requires Golgi reassembly stacking protein (GRASP) and vesicular components linked to secretory autophagy, a nondegradative autophagic process promoting the trafficking of cargo to the plasma membrane

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