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This powerful medication is FDA-approved for chronic weight management in adults who are obese or overweight with a weight-related condition

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Semaglutide is commonly prescribed to men and women with a Body Mass Index (BMI) of 30 or above, or to individuals with a BMI of 27 or more who also have high blood pressure, type 2 diabetes, high cholesterol, or other conditions that make losing weight more challenging

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This study was underpowered to detect a difference in carriers of p.S539W and did not demonstrate a significant difference (1340 220 vs