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More Than Just Weight Loss: How GLP-1 Agonists Evolved from Diabetes Drugs to a New Class of Metabolic Medicines When GLP-1 receptor agonists (GLP-1RAs) were first approved over a decade ago, their primary indication was simple: help people with Type 2 diabetes manage their blood sugar

Members of the tyrosine kinase receptor superfamily including epidermal growth factor receptor (EGFR), insulin growth factor receptor 1 (IGFR1), and fibroblast growth factor receptors (FGFRs) are some of the factors involved [49]

Timms et al