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Several FDA-approval drugs will be discussed, including liraglutide, semaglutide, tirzepatide, orlistat, and combinations like phentermine/topiramate and bupropion/naltrexone, noting their effectiveness in obesity management [34, 35] (Table 1)

However, some people worry that semaglutide might have direct effects on nerves that could cause pain

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For ASM participants that receive a final score of zero as described at 512.745(a)(2)(ii), calculate the ASM payment adjustment factor for each ASM participant equal to the negative of the applicable ASM risk level as described at 512.750(c)(1)(i)