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Description

Semaglutide works by mimicking a hormone called GLP-1 (glucagon-like peptide-1) that targets areas of the brain responsible for regulating appetite and food intake

Such variability inevitably weakens observed correlations and reduces the proportion of explained variance

The result is largely based on the systematic evaluation at the Icahn School of Medicine at Mount Sinai

These insights may help contextualize individual GLP-1 pathway biology and support a more informed conversation with your provider about medication selection and expected outcomes

Nature , 432(7016), 466472

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