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doi: 10.1126/science.1124234 79 Gomez-ArangoL

By activating the Beclin-1 pathway and inhibiting mTOR, melatonin improves the clearance of pathological forms of -synuclein, which limits their toxic effects on nerve cells [148,149,150,151,152]

The core process of autophagy is linked to the regulation of two kinases: mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK) [210]

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