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Similarly, intestine-specific Znt10 KO revealed moderate systemic Mn accumulation, whereas intestine and liver double Znt10 KO resulted in severe Mn overload compared to either KO alone (Mercadante et al., 2019), suggesting that both intestine and liver ZNT10 play an essential role in Mn excretion

Krogholm KS, Bredsdorff L, Knuthsen P, Haraldsdttir J, Rasmussen SE

GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring tripeptide-copper complex first identified in human blood plasma

These seemingly paradoxical effects may be one explanation for why patients with G6PD-d display increased susceptibility to infection indicative of an impaired immune response, while also displaying increased autoimmunity and inflammation indicative of an overactive immune system 13

Astragalosides (from Astragalus membranaceus) and glycyrrhizin (from Glycyrrhiza uralensis) have shown vasoprotective effects as well, by ameliorating endothelial dysfunction and oxidative damage (Wang Y