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The group on semaglutide only experienced 794 fractures, while the control group experienced 1,045
As obese subjects appear to display a more rapid gastric emptying of solids compared to normal weight subjects (86) and the natural increase in plasma GLP-1 is attenuated in obese subjects (86, 87), the smaller release of GLP in the obese subjects could cause less pronounced satiety of food intake, leading to earlier onset of the next meal
Furthermore, extensive clinical trials with Ozempic have revealed significant cardiovascular benefits, including a reduced risk of major cardiovascular events, such as heart attacks and strokes, in patients with type 2 diabetes who have cardiovascular risk factors
December 17, 2016
doi: 10.1093/ckj/sfae018
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