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Specifically, activating MCRs centrally in APP/PS1 murine models possibly reduces amyloid plaque formation and decreases levels of both soluble and insoluble A in brain regions like the hippocampus and cortex

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However, the majority of patients in literature presents in adolescence or adulthood with myopathy as first complaint [106]

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J Ophthalmol 2015;2015:1-10