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Patients with SLE exhibit decreased Treg cells and compromised function in alongside a higher proportion of Th17 cells, which is positively correlated with the severity and advancement of the disease (218, 219)

Thiocyanate, a byproduct of cyanide detoxification, can also harm the thyroid gland by competing with iodine, though this is generally observed only in populations exposed to high levels of cyanide through occupational sources or diets extremely high in cyanoglycosides, typically in regions with low soil iodine (Amar, 2015)

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