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In a randomized, double-blind, placebo-controlled study, the use of dexpanthenol pastilles (300 mg/day for up to 14 days post surgery) was found to accelerate mucosal healing after tonsillectomy in children (27)

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IGF-1 LR3 acts at the opposite end of that axis, as an exogenous receptor agonist applied directly at the endpoint, bypassing the feedback control entirely

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Its mechanisms include modulation of neurotransmitter signaling that promotes slow-wave activity, reduction of nighttime cortisol and stress hormone interference with sleep architecture, and support for the timing and depth of the sleep cycle itself