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These compounds interact with receptors on L-cells, triggering signaling pathways that stimulate the secretion of GLP-1

Its crucial to note that individuals with diabetes are not eligible for the Bridge program, as diabetes-related treatments should already be covered by existing health plans

Also, patients with pregnancy, breast feeding, patients suffering from endocrine diseases, autoimmune disorders, chronic debilitating diseases like malignancy, decompensated cardiac, pulmonary, renal, or hepatic diseases were ruled-out

In rodent studies, semaglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

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