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& Ang Ling, E

Inui, 2001), with both increasing AMP-activated protein kinase (AMPK) activity in the hypothalamus and reducing it in the liver and adipose tissue (Kola et al., 2005)

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Additionally, small-molecule inhibitors, such as retinoic acid receptor-related orphan receptor gamma-t (RORt) inhibitors (e.g., VTP-43742) and tyrosine kinase 2 (TYK2) inhibitors (e.g., deucravacitinib), are currently in development