mazdutide vs semaglutide (IBI362): The Next-Generation Dual GLP-1/Glucagon Agonist for Obesity and Metabolic Health Mazdutide: Entry #22 of 100+

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These findings align with global analyses from Europe, North America, and Asia reporting similar population-level increases in vitamin B12 deficiency, where prevalence ranges from 5 to 20% depending on age, diet, and socioeconomic status

However, mechanistic clues claiming either copper deficiency or copper build-up (associated with hydrazide formation-dependent enzyme inhibition) remain contradictory [306]

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