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Furthermore, the study identified specific microbial metabolites (such as deoxycholate) that stimulate EC cells to upregulate TPH1 expression and promote 5-HT synthesis

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Fifth, GLP-1RAs protect against cardiomyocyte apoptosis under diabetic conditions via activating the leucine zipper motif (APPL 1 )-AMPK-PPAR axis and the AMPK-TXNIP pathway [80, 161]

| Ian Somerhalder