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Dysregulation of HSP60 is a hallmark of metabolic disorders, with elevated circulating HSP60 levels linked to insulin resistance and cardiovascular complications in T2DM patients

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Unlike earlier weight-management medicines, retatrutide simultaneously targets three distinct hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor