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The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects

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Plat AW, Rasouli N, Peleshok J, Sapin H, Wilding J (2022) Change in body weight from baseline with tirzepatide: sex subgroup analysis of the SURPASS studies

What time of day you take Wegovy does not matter, as long as you stick to the same time for each weekly dose