I've been watching case Iron on YouTube and he seems to know his shit but I can't take one source as legitimate material to follow
In HCECs applied with desiccating stress, the CEC ferroptosis was triggered by the aggregation of autophagy impairment-derived sequestosome 1 (SQSTM1), the overexpression of which fostered ferroptotic changes and substantially elevated ACSL4 (124)
Melanotan-2: The Shotgun Approach MT-2 hits the same MC1R receptor but also activates MC3R, MC4R, and MC5R : MC1R Melanin production (tanning) MC3R Energy homeostasis, cardiovascular function MC4R Sexual arousal, appetite regulation, erectile function MC5R Exocrine gland function, sebaceous secretion This non-selective binding is why MT-2 causes the "side effects" that many users actually seek out particularly the libido and appetite suppression effects
The most commonly reported issues are gastrointestinal in nature
This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders