Key Takeaways GGT is more than a liver enzyme It reflects oxidative stress, detox burden, and metabolic risk Elevations often occur before overt disease Alcohol, insulin resistance, and inflammation are major drivers Integrative strategies can meaningfully lower GGT The Bigger Picture Elevated GGT is not a diagnosis
Additionally, a recent study (198) suggests that R-SH, an OSM, could serve as a biomarker for IBD, proving more sensitive than C-reactive protein (CRP) in detecting moderate endoscopic activity, though less sensitive than fecal calprotectin, with age and albumin levels as potential confounding factors, and indicates that R-SH may improve IBD monitoring
PRODH is transcriptionally regulated by p53 and plays important roles in apoptosis, autophagy and cellular stress adaptation, particularly under nutrient deprivation or oxidative stress 61,62
NAD+ is a cellular energy and repair coenzyme that works broadly across every cell, supporting mitochondrial energy production and DNA repair enzymes
Published research also shows GHK-Cu promotes wound healing, reduces fine lines, and supports skin density