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Not everyone needs to climb to 15 mg

That single extra receptor, the glucagon receptor, changes everything about how the body burns fat, processes liver lipids, and preserves metabolic function during aggressive weight loss

These observations collectively highlight the need for further investigations and attentive post-marketing surveillance

Last updated 10/2025

Key monitoring parameters include: Thyroid function tests : TSH and free T4 levels to confirm adequate thyroid hormone replacement Body weight : Regular weight monitoring is standard when using Mounjaro for diabetes or weight management Blood glucose levels : For patients with type 2 diabetes, monitoring glycaemic control through HbA1c and self-monitoring of blood glucose as recommended in NICE guidance (NG28) Symptoms : Attention to symptoms of either hypothyroidism (fatigue, cold intolerance, constipation) or hyperthyroidism (palpitations, anxiety, tremor), which might indicate suboptimal thyroid hormone levels Precautions for hypothyroid patients taking Mounjaro include maintaining consistent medication timing, particularly for levothyroxine