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Phase Ia trial of murine immunoglobulin A antitransferrin receptor antibody 42/6

Both in vitro and in vivo data in rodent studies indicate that NSI-189 is capable of stimulating hippocampal neurogenesis, which has been proposed as a potential mechanism for antidepressant drug function

Sensitized mice are highly susceptible to rUTIs upon challenge, with robust sustained bladder TNF and Cox-2 expression causing neutrophil transmigration across the bladder epithelium (urothelium) and mucosal wounding that promotes severe recurrent bacterial infections 6,7,8

The occipital artery and the pterygopalatine artery (PPA) were permanently ligated

doi: 10.1016/j.cger.2021.07.011 8 CarrollKM