Both medications typically need consistent use over weeks or even months before any significant changes become apparent, which can feel discouraging for some
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At peripheral levels, the administration of GLP-1 RA regulates follicular proliferation and apoptosis-induced follicular atresia of the granulosa cells, a key component of the dominant follicle selection, possibly contributing to the oocyte maturation in PCOS
Additionally, Finland studies have indicated its regenerative actions, including the stimulation of blood vessel and nerve outgrowth, synthesis of collagen, elastin, and glycosaminoglycans, support for immune function and nervous system
You can start treatment without waiting on blood work, which is a plus for patients who want to move quickly