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Written By Martin Weaver, MD Dr
Al, obese Zucker rats were received a dose of 500 micrograms/kg of body weight over the course of 19 days
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NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores
Key determinants include: Diet composition, including fiber, micronutrients, and bioactive compounds
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