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Also, consider how your team will manage or dispose of existing stock of compounded semaglutide injection products that are not dispensed before the FDA enforcement date

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Relative contraindications requiring careful consideration and enhanced medical supervision include history of pancreatitis, severe gastrointestinal disease including gastroparesis, diabetic retinopathy (requires ophthalmologic monitoring during therapy), severe kidney disease, history of suicidal ideation or severe depression, gallbladder disease or history of cholecystitis, and age under 18 years

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Among the 101 participants receiving the highest 4.5 mg/week dose, the most frequently reported side effects included: Indigestion: 4% Headache: 7% Loose stools: 7% Vomiting: 8% Allergic reactions: 10% Fatigue: 20% Constipation: 21% Injection site reactions: 43% Nausea: 47% Serious side effects in this phase 2 trial occurred in 2% to 7% of the cagrilintide groups, compared to 4% in the liraglutide group and 3% in the placebo group

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