Han W, Zhang B, Zhao W, Zhao W, He J, Qiu X, Zhang L, Wang X, Wang Y, Lu H, Zhang Y, Xie Y, Geng Y, Zhao W, Huang Q, Zhang Y-W, Wang Z (2025) Ketogenic -hydroxybutyrate regulates -hydroxybutyrylation of TCA cycle-associated enzymes and attenuates disease-associated pathologies in Alzheimers mice
Indeed, a 2019 literature review discussed berberines potential for antitumor effects against a few types of cancer, and a more recent review from 2024 highlighted its ability to support chemotherapy.13 49 At this time, the most extensive research on berberine has revolved around its impacts not on cancer but on diabetes and cholesterol management, so those are the health concerns for which the supplement is most likely to yield benefits
therefore, diagnosis is primarily clinical, although it may be aided by validated questionnaires, neurophysiological examination, as well as imaging studies [10]
Western blots were visualized using an ECL kit (Perlcin Elmer In
Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25
