Am J Physiol Gastrointest Liver Physiol 281(5):G1135G1139 Roman J, Colell A, Blasco C, Caballeria J, Pares A, Rodes J, Fernandez-Checa JC (1999) Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB
For example, when upregulated expression of drug-resistance genes (e.g., Mdr1/Abcb1) in the intestinal flora is detected, the risk of antibiotic use can be flagged in advance to prevent exacerbation of bacterial resistance
Particularly in bladder cancer, alterations in mitochondrial dynamics are not only associated with the migratory and invasive abilities of tumor cells but also likely serve as key driving factors for tumor cell metastasis from the primary site to other tissues
(4) multi-omics integration combining metabolomics with metagenomics, transcriptomics, and proteomics to build mechanistic causal models
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