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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) New England Journal of Medicine 389(24) 2023PMID: 37952131 NEJM 5 Ryan DH, Yockey SR Weight Loss and Improvement in Comorbidity: Differences at 5%, 10%, 15%, and Over Current Obesity Reports 6(2) 2017PMID: 28455679 PubMed References open in a new tab

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Creatine supplementation causes intracellular water retention in muscle tissue, which accounts for initial weight gain of 2-4 pounds

Gong N, Xiao Q, Zhu B, Zhang CY, Wang YC, Fan H et al (2014) Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity