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Methods Data Source EHR and prescription data were extracted from the IBM Explorys EHR database (IBM Watson Health, Armonk, NY, USA), allowing clinical outcomes to be linked to treatment use

Cardiovascular Health : Some studies suggest that GLP-1 analogues may have cardioprotective effects , improving cardiovascular health by regulating lipid levels , blood pressure , and inflammatory markers

Additionally, we ensured that both the non-GLP-1 RA and GLP-1 RA treatment cohorts had similar mean follow-up times (75.9 months, SD = 37.5 and 75.8 months, SD = 37.9, respectively) to control for lead-time bias

Other trials are now exploring novel indications, including for fatty liver disease or to optimize metabolic health in individuals with various backgrounds

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