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Claims made online often go much further than the strongest available evidence supports, especially when preclinical findings are casually translated into human outcomes

To deal with some of these challenges, a versatile CPP-based delivery system has been developed and assessed for its effectiveness and safety (Xie et al., 2020)

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For controlled skin studies, topical application removes the confounders introduced by injection no injection site reactions, no systemic distribution diluting local concentration, no injection technique variability across research subjects