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H., Leung, C

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J Inherit Metab Dis 44:13931408

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103 Whether these differences lead to differing patterns of clinical effectiveness is uncertain

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As biofilms can increase the antibiotic resistance of bacteria up to 1,000-fold (Hiby et al., 2010), therefore the dissolution or prevention of these biofilms is an important part of the host antimicrobial defense and presents a challenge to both the host immune system and also the therapeutic development

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The trade-off is technique responsibility patients must learn proper subcutaneous injection and sterile handling to achieve clinic-equivalent safety

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