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Among adults with the highest category of obesity, about 4% used GLP-1 medications in 2008, and 33% did by 2023 an 800% increase

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Significant weight loss, particularly rapid weight loss, can temporarily disrupt the hypothalamic-pituitary-ovarian (HPO) axis, the hormonal feedback loop that regulates ovulation and menstruation

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In the Y-maze test, the control group presented significantly fewer altered triplets than the WT group did ( P = 0.0001