Additional comparison was made with targeted protein measurements of serum samples from age- and sex-matched autoantibody-negative unaffected family members (UFMs, n =194)
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These observations qualified the HepG2 model to study the mechanisms described herein
J Biol Chem 276:29596602 Fratelli M, Demol H, Puype M, Casagrande S, Eberini I, Salmona M, Bonetto V, Mengozzi M, Duffieux F, Miclet E, Bachi A, Vanekerckhove J, Gianazza E, Ghezzi P (2002) Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes
Gluten sensitive enteropathy, for example, results in inflammation of the bowel surface, which reduces the bowels absorption of a variety of nutrients (including iron)