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Vasoactive intestinal peptide (VIP) VIP belongs to the glucagon/secretin gene family, with its own VIP gene that transcribes to two prepro-VIP precursors, giving rise to 3 peptides (in humans) VIP, peptide histidine methionine 27 (PHM-27) and peptide histidine methionine 42 (PHV-42) [111]

These morphological changes decrease astrocytic presence in the neuropil and hence diminish their homoeostatic support of the nervous tissue

Understanding the mechanisms and research surrounding this deficiency can shed light on its impact on mood disturbances such as anxiety and depression

Perioral lesions and dermatoses

The appropriate peptide concentration, at the recommended dose, brings the expected supportive effect