They are often marketed under the brand names Victoza or Saxenda, Ozempic or Wegovy and Mounjaro or Zepbound, respectively
Designed for adults with a BMI of 30 or higher, or 27 and higher with weight-related conditions, Wegovy offers significant weight reduction, with clinical trials showing a 15% average weight loss over 68 weeks
Before the study began, all patients had magnetic resonance imaging (MRI) to evaluate brain structure and volumes, glucose metabolism PET scans and detailed memory testing
These findings suggest that GLP-1R-independent renoprotective effects are mediated by GLP-1 cleavage products
These medications slow gastric emptying and reduce appetite, which means patients often experience changes in their eating patterns, portion sizes, and food preferences