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Here are some of the basics about injecting semaglutide: DO inject it just under your skins surface, ideally into fat, such as into your stomach, upper arm, or thigh rotate injection sites, changing the site for each dose inject it at least 2 inches away from your belly button (navel) when injecting into your stomach AVOID injecting it into your veins or muscles injecting it into areas that are red or have other color changes, bruised, or tender injecting it into areas with stretch marks or scars If you use insulin, you may inject semaglutide into the same area of your body as insulin, but you should not inject one right next to the other