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Recent studies have showed that oral ingestion of L-carnitine in both animals and humans results in generation of trimethylamine by intestinal microbiota, which is absorbed and then metabolized to trimethylamine-N-oxide (TMAO) by liver flavin monoxygenases (FMOs) (especially FMO3 and FMO1) 35,45

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The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies*

Usually not in single-vial quantities

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