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By administering a weekly injection, Ozempic effectively manages type 2 diabetes through the following mechanisms: Facilitating insulin secretion to ensure proper glucose absorption during digestion, thereby maintaining stable blood sugar levels throughout the process

In preclinical models, it increases insulin release and decreases glucagon, which is the activation of GLP-1 receptors

The mechanics: if the parent application was published either as a published application or as an issued patent more than one year before the CIPs filing date, and if the CIPs claims rely on new matter such that they carry only the CIPs later filing date, then the published parent document constitutes statutory prior art