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Based on studies employing food frequency questionnaires, the average dietary intake of coenzyme Q 10 is about 3 to 6 mg/day (97)

The MHRA SmPC notes that animal studies have shown C-cell tumours in rodents, though the human relevance is uncertain

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it is whether the systemic exposure floor in humans, after dose escalation, accidental linker leakage, and long-term cumulative effects, stays below the threshold that triggers the historical PPAR liabilities

Avoid injecting into the same spot within at least 2 inches of a previous injection site