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Pharmacokinetic studies in humans have found that about 30%-40% of an oral dose of a racemic mixture of R -lipoic acid and S -lipoic acid is absorbed (6, 7)

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The molecular clock machinery is found in most cells and, thus, for coherent timing, different tissue clocks are synchronized by a master pacemaker located in the suprachiasmatic nucleus (SCN) of the hypothalamus 1,2

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