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The study investigated a topical application of GSH-cyclodextrin nanoparticle complex (Glutaryl) as a potential non-invasive GSH delivery route with therapeutic effects against mycobacterium infection

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Ferroptotic injury promotes the release of pro-inflammatory mediators and amplifies oxidative stress (79), which can aggravate microcirculatory dysfunction and hypoxia, thereby reactivating HIF programs and further perturbing iron handling

The alcohol-based formulas can be harsh, especially with twice-daily application