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Those who thought it would have a negative impact were mostly Gen Z (63%)
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Science 322, 449452
A second group, those with gastroparesis, severe kidney disease, or active eating disorders, requires careful provider evaluation before starting
Further, GLP-1RAs promote VSMC redifferentiation via AMPK/SIRT1/forkhead box O (FOXO3a) pathways, where the expression of contractile VSMCs markers (SM22 and Calponin) is increased [125]
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