glutathione is a steroid or not Chemical structure of (GSH; γ-Glu-Cys-Gly). In dGSH, the Glutathione System from Cyanobacteria to

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demonstrated that erastin-induced ferroptosis elevated lysosome-associated membrane protein 2a (LAMP2a) expression and promoted chaperone-mediated autophagy (CMA) while facilitating GPX4 degradation, suggesting a possible connection between autophagy and ferroptosis ( c thereby inducing ferroptosis in addition to inhibition of NF-B pathway ( 1S,3R )-RSL3 forms covalent bonds with GPX4, which is inactivated via alkylating the selenocysteine and leads to toxic lipid peroxides buildup, and inevitable cell death (Yang et al., 2014