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2008 Feb;83(2):97-102

There are very many small signs, seemingly of little matter, but in reality of very great importance, such as stars, crosses, squares, and triangles, little marks with frequently great meanings

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The sentiment is echoed again in Clarissa's thoughts at the end of the novel, when the elderly Laura Brown comes to visit having heard that her son, and Clarissa's close friend, Richard, has died: "Here is the world, increasingly managed by people who are not you"

Additionally, loneliness is linked to a higher incidence of dementia (4 Trusted Source Does loneliness contribute to mild cognitive impairment and dementia